Accidental ingestion of even a person dose, particularly in small children, may end up in a lethal overdose of oxycodone.
Advise both of those individuals and caregivers concerning the pitfalls of respiratory depression and sedation when oxycodone HCl is made use of with benzodiazepines or other CNS depressants (together with Liquor and illicit medication). Suggest people to not push or run unsafe machinery till the consequences of concomitant use on the benzodiazepine or other CNS depressant have been established.
When having oxycodone HCl tablets: Tend not to adjust your dose. Take oxycodone HCl tablets precisely as prescribed by your healthcare supplier. Use the bottom dose possible for the shortest time desired.
Sedation which could impair your reaction skills and have an impact on your ability to drive or operate machinery. Stay clear of alcohol as The mixture can result in perilous or fatal Unwanted side effects. Other prevalent Uncomfortable side effects consist of constipation, dizziness, nausea, vomiting, and confusion.
Oxycodone HCl may well trigger extreme hypotension including orthostatic hypotension and syncope in ambulatory people. There exists elevated possibility in sufferers whose ability to take care of hypertension has presently been compromised by a lowered blood quantity or concurrent administration of selected CNS depressant medicines (e.
Recall, preserve this and all other medicines out in the access of youngsters, under no circumstances share your medicines with Other individuals, and use oxycodone only for the indication prescribed.
Oxycodone chloride can gradual or cease your respiratory. This is more most likely in elderly or sick patients check here but can arise in anyone getting this medicine.
Since aged individuals are more likely to have lowered renal function, care should be taken in dose selection, and it may be useful to watch renal operate.
Oxycodone HCl tablets USP, 20 mg are equipped as grey, round, biconvex tablets debossed with "A" within the remaining and "fifty" on the right on the score on one aspect and simple on the other aspect.
Any one should purchase naloxone from a pharmacy or neighborhood health and fitness department. Ensure that any person caring for you personally is familiar with where you retain naloxone and the way to use it.
Retailer oxycodone HCl tablets securely, out of sight and attain of kids, As well as in a location not obtainable by Many others, including visitors to the home.
Because oxycodone is known to be significantly excreted via the kidney, its clearance could decrease in individuals with renal impairment.
Mutagenesis Oxycodone hydrochloride was genotoxic within an in vitro mouse lymphoma assay during the presence of metabolic activation. There was no proof of genotoxic likely within an in vitro bacterial reverse mutation assay (Salmonella typhimurium and Escherichia coli) or within an assay for chromosomal aberrations (in vivo mouse bone marrow micronucleus assay).
Withdrawal from oxycodone is likely to happen to people who have taken oxycodone persistently or misused oxycodone. Typical signs and symptoms of withdrawal involve: